Tempris, an innovation leader in wireless in-process product temperature control for freeze-drying, is delighted to announce that it has been presented with the 2025 ISPE Robotics Applications of the Year (RAYA) award in the “Drug Product” category for its closed-loop temperature control, which provides continuous product temperature monitoring and endpoint determination of primary drying to reduce freeze-drying losses, speed up production, and increase margins.
The manufacture of sterile injectables is one of the most demanding processes in the pharmaceutical industry, and freeze-drying plays a key role in this process. Yet almost 100 percent of parenteral drugs are currently manufactured without continuous product temperature monitoring—a common cause of quality defects and batch losses. Tempris closed-loop control is revolutionising pharmaceutical freeze-drying by combining wireless real-time temperature measurement, robot-assisted aseptic sensor placement, and the intelligent LyoCLC® control software.
Precise monitoring, higher quality, lower costs
The jury was particularly impressed by the battery-free, real-time temperature monitoring, the automated workflows using robots, as well as the strict compliance with regulatory requirements and guaranteed traceability, which take the freeze drying of sterile injectables to a new level by removing the need for speculation and excessive safety margins, and instead providing the means for data-driven decisions and maximised efficiency. With Tempris’ closed-loop control, manufacturers achieve:
• Up to 30% shorter drying times with reproducible product quality
• Faster product launches – 40-50% reduction in time-to-market
• Lower manufacturing cost of goods (COGs) and improved margins
• Shortened return on investment (ROI) to below 1.3 years and, in the event of deviations, even positive returns within a few months.
