SPT Labtech, a global leader in the design and development of laboratory automation and liquid handling solutions, has announced the availability of validated automated workflows for Twist Bioscience’s next-generation sequencing (NGS) library preparation kits on its firefly® liquid handling platform.
Developed through a collaboration with Twist Bioscience, the workflows are designed to support higher-throughput, more reproducible NGS library preparation and are accessible directly through the firefly cloud.
Development of these workflows reflects growing demand across genomics research and core facilities for standardized automated protocols that improve consistency while reducing hands-on time as sequencing volumes continue to increase.
The initial validated automated workflow supports Twist Bioscience’s FlexPrep™ UHT Library Preparation Kit on SPT Labtech’s firefly platform.
The automated FlexPrep™ workflow is designed to streamline NGS library preparation through on-deck fragmentation and ligation, as well as an auto-normalising protocol that reduces indexing and final cleanup to four columns of a 96-well plate.
This approach enables increased throughput for laboratories that do not have access to a 384-well thermal cycler, while supporting more consistent processing across samples.
The collaboration also integrates the Twist Enzymatic Fragmentation Kit 2.0 with firefly, enabling an efficient sequencing pipeline, reduced error rates and more accurate results.
Ongoing combination of Twist NGS library preparation kits with firefly will continue to expand SPT Labtech’s portfolio of validated, easy-to-implement automated workflows, increasing global access to innovative tools for genomics research.
The automated workflows are available immediately via the firefly cloud for firefly users.
